While this isn't an answer to why this happened, is it possible for you to check the box to Enable DNS blocklists and then pick a list from the drop down menu. Apply those settings and let the list download. Then go back, de-select the blocklist and uncheck the "enable" box for the block lists?
This might 'reset' whatever odd config is causing these to run?
This might 'reset' whatever odd config is causing these to run?