Another DNS Blocklist Question: OISD w/Blocklist.site Targeted Lists

[House Of Cards]

Good evening,

I am currently using the OISD Big List, which says it blocks various categories of bad things.  I like that I haven't had issues, but I want to supplement that with the categories available in OPNSense from Blocklist.site.  I can't find any real information between the two, and it doesn't look like the OISD list contains any of those lists.

I am considering leaving the OISD for the default ad/tracking protection, since it works.  And then supplement with the specific Malware/Scam/Abuse type categories for greater protection.  When I do this, I add over 1 million sites to the list, so I was wondering if anyone has any experience with these Blocklist.site lists, and if they break everyday browsing.

To be clear, I am NOT looking to implement the Blocklist.site Ad/Tracking lists...  I would leave that for OISD.  I just want to have a comprehensive list of bad-guy sites.