Did you put the LAN network into the allowed IPs in each client, additionally to the wireguard network?So for example if your wireguard network is 10.4.4.0/24, and your LAN is 192.168.1.0/24, the allowed IPs on the clients should be 10.4.4.0/24 192.168.1.0/24Also make sure to use a unique port per instance. If instance wg1 is 51820, instance wg2 should be 51821 etc...- Yes your setup is possible, you can have multiple wg instances with different settings attached to them. I'm not sure about sharing peer configurations between them though, I have always created unique peers because things like "allowed IPs" change when you have multiple instances, and the routing in the firewall depends on this uniqueness.