Sounds like your Unbound can't verify certificate (yes, you need a certificate)
Make sure you have typed correct certificate name (in DNS over TLS settings, edit cloudflare dns record and you should see "verify CN" field), you can find correct record using dig command on linux or nslookup on windows (just type dig/nslookup IP_ADDRESS and you should see the certificate name as a result. Correct one for 1.1.1.1 is "one.one.one.one" without quatation marks, but not sure about other IPs)
This is easy to miss since on WebUI, verify CN isn't visible anywhere else, other than creation or edit window.
Make sure you have typed correct certificate name (in DNS over TLS settings, edit cloudflare dns record and you should see "verify CN" field), you can find correct record using dig command on linux or nslookup on windows (just type dig/nslookup IP_ADDRESS and you should see the certificate name as a result. Correct one for 1.1.1.1 is "one.one.one.one" without quatation marks, but not sure about other IPs)
This is easy to miss since on WebUI, verify CN isn't visible anywhere else, other than creation or edit window.