Packet loss and ssl connection errors

[runo10]

Hello,

I have a r210 II-1240v2 server as a opnsense firewall with "Intel(R) I350 (Copper)" ethernet card. I use transparent bridge mode
I have got packet loss problems.
I have tried many things.

I make all offloads disabled and this tunables:
dev.igb.0.eee_disabled 1
dev.igb.0.fc 0
net.isr.bindthreads 1
hw.igb.tx_process_limit -1
hw.igb.rx_process_limit -1
net.isr.dispatch deferred 
net.link.bridge.pfil_onlyip 1
net.inet.udp.checksum 1
net.inet.tcp.tso 0
No hardware acceleration

That settings not worked much. I have tried these and it is much better now nearly solved:

all interfaces mtu 1450, mss 1412
firewall normalization-> mss clamping 1410
use powerd and maximum setting for all
dev.igb.0.eee_control 0
hw.igb.enable_aim 0
legal.intel_igb.license_ack 1
 
But it gives 1-2/1000request timeouts(timeout threshold 5sec) in country network. (https request)

And it gives nearly 1 ssl connect error on global network per hour at better stack(uptime checker)(https request)


And gives no error for ping requests at global network for now.
Any idea?